Slide Shows?

I've been toying around with the idea of building my site around the framework of a slideshow.

I figured this would be a slick and intuitive way to present my story.

However, upon further research it has become clear to me that the use of a slide show may complicate what should be a relatively straight forward idea. Firstly, a slide show would make sound cues harder to implemented. furthermore I intend to use hotspots on my images in order to give the audience an interactive experience whilst advancing the plot in more engaging ways. As far as I'm aware slide shows do not support this function.

What I intend to do instead is create a separate webpage for each 'panel' of the story. this will give me greater flexibility, enabling me to alter the aesthetic site on a page by page basis.